Jakob Hoffmann, a merchant in Ludwigsburg, was not satisfied with this outcome. He challenged his son Felix, an up-and-coming chemist, to find out the cause of the problem. At the time, Felix was working in the scientific laboratory of the pharmaceutical company Farbenfabriken vorm. Friedr. Bayer & Co. in Wuppertal- Elberfeld. He went to work immediately. The experiment in which he reacted salicylic acid with acetic acid finally yielded the desired result: acetylsalicylic acid. Hoffmann produced this substance synthetically for the first time on August 10, 1897. Under the brand name Aspirin, acetylsalicylic acid became one of the bestknown medications of the modern era. Aspirin was initially sold in bags in powder form, but in 1900 Bayer launched this active ingredient on the market in the form of tablets containing 500 mg of acetylsalicylic acid.